Friday, 5 February 2021

Telomeres - Health and ageing

 What is telomere and its function?

Telomeres are specialized nucleoprotein structures located at the ends of linear chromosomes; they consist of TTAGGG repetitive sequences. They function to prevent natural chromosomal termini from activating the DNA damage response

Their job is to stop the ends of chromosomes from fraying or sticking to each other, much like the plastic tips on the ends of shoelaces. Telomeres also play an important role in making sure our DNA gets copied properly when cells divide.


What is the role of telomeres in aging?

Telomeres get shorter each time a cell copies itself, but the important DNA stays intact. Eventually, telomeres get too short to do their job, causing our cells to age and stop functioning properly. Therefore, telomeres act as the aging clock in every cell.


How can I regrow my telomeres?

5 ways to encourage telomere lengthening and delay shortening

Maintain a healthy weight. Research has found obesity as an indicator of shorter telomeres. ... 

Exercise regularly. ... 

Manage chronic stress. ... 

Eat a telomere-protective diet. ... 

Incorporate supplements.


It highlights the importance of Dinacarya, Ritucarya and Sadavrtha as well as the action of Rasayanas

What foods increase telomeres?

Telomere length is positively associated with the consumption of legumes, nuts, seaweed, fruits, and 100% fruit juice, dairy products, and coffee, whereas it is inversely associated with consumption of alcohol, red meat, or processed meat .


What is a telomere diet?

Research shows that those with higher levels of antioxidants such as Vitamin C, E and selenium tend to have longer telomeres. Fruits and vegetables are the best sources of antioxidants, which is why a plant-based diet is highly recommended.


Does exercise lengthen telomeres?

Telomerase activity was increased two- to three-fold and telomere length was increased significantly in the endurance and high intensity training groups compared to the resistance and control groups. “The study identifies a mechanism by which endurance training – but not resistance training – improves healthy aging.

Does yoga lengthen telomeres?

Telomeres, located at the tips of DNA chromosomes, shorten with aging and age-related diseases including cancer, cardiovascular disease and diabetes. ... The following studies have found yoga and meditation can protect and even lengthen DNA telomeres

Yoga is an excellent anti-aging tool, capable of relieving symptoms and in some cases improving medical outcomes. It doesn't matter where you're starting from or how old you are—movement and yoga can help.


When should I not do yoga?

Yoga should not be performed in a state of exhaustion, illness, in a hurry or in an acute stress conditions.

Women should refrain from regular yoga practice especially asanas during their menses. ... 

Don't perform yoga immediately after meals. ... 

Don't shower or drink water or eat food for 30 minutes after doing yoga.

Yoga should not be done without the guidance of a certified trainer.